Epithelial carcinoma of the ovary or Ovarian cancer is
one of the most common gynecologic diseases. It is serious
and has a very high mortality rate. It is the fifth most
frequent cause of cancer death in women. It is most common
in women above fifty years of age. The cancer can appear in
younger women too. It is seen that women having genetic
predisposition are at greater risk. Clinical statistics
also show less cases of this malignancy in women using
contraceptive medication. Women who have had early
pregnancy or have more children also seem to be at a lower
risk factor.
Prognostic factors are used to predict the likely course
of ovarian cancer. Stage is the only unanimously
acknowledged prognostic factor for patients with ovarian
cancer. In case of advanced stage patients, volume of
residual disease is considered as a diagnostic factor. To
begin a prognosis and establish treatment, the physician
needs to know the cell type, stage, and grade of the
disease. Other factors that may be important include the
patient?s age, histopathologic grade, DNA ploidy,
Peritoneal fluid cytology and CA125.
The International Federation of Gynecology and
Obstetrics (FIGO), has created standards for the staging of
gynecological cancers. Both surgical and pathological
findings are taken into account, hence it is called
surgicopathologic.
Most ovarian cancer symptoms are seen only in the late
stages of the disease. Ovarian cancer is treated with
surgery to remove the cancerous cells. This is followed by
chemotherapy. It is recommended that people experiencing
vaginal bleeding, uncharacteristic period cycles, or
intestinal problems should see a physician right away, so
that such cases can be detected at the earliest.
Unfortunately, like most of the cancers, the exact cause
of ovarian cancer is not known. It is also difficult to
find precise information due to contradictory studies.