Stage III ovarian cancer is a more serious level of
cancer, which has spread to include the pelvic area and
organs, and the abdominal organs (liver, bowels, lymph
nodes, etc.), and it is easier to diagnose. It is used as
part of the prognosis made by a doctor.
Stage III ovarian cancer is then further defined by the
TNM determination rating system. TNM is defined to mean to
tumor size, node inclusion, metastasis or spread status and
grade of the tumor. It will ultimately let doctors known
how long a patient has to live and whether they will
survive. These factors include:
Each part is defined as follows:
TNM determination rating system
Tumor size – Due to the spread of Stage III, the
tumors can only be defined as one of the following:
T3: the tumor is inside one (or both) ovary; the tumor
spread includes tissues in the pelvic region, outside the
pelvic region and lymph node (s); cancerous cells are found
in the abdominal fluids (ascites) or the abdominal cavity
washes (peritoneal lavage)
T3a: the tumor is inside one (or both) ovary; the tumor
spread includes tissues in the pelvic region, outside the
pelvic region and beyond the pelvic region
T3b: the tumor is inside one (or both) ovary; the tumor
spread includes tissues in the pelvic region, outside the
pelvic region and beyond the pelvic region that are now a
maximum size of up to 2cm, and can be seen without a
microscope
T3c: the tumor is inside one (or both) ovary; the tumor
spread includes tissues in the pelvic region, outside the
pelvic region and beyond the pelvic region that is now a
2cm or more in size, and can be seen easily
Node inclusion – As the cancer is at Stage III
its classification is:
N1: the tumor has spread to include the lymph nodes
Metastasis or spread determination – As Stage III cancer
has been found, only the following classification can be
used:
M1: metastases have been found somewhere
Grade of the tumor
The grading of a tumor shows the maturity of the
cancerous cells inside the ovary (s). As the cancer is now
at Stage III, it can only be classified as the
following:
Grade 2: a combination of both normal and cancerous
cells; cancerous cells account for about every other
cell
Grade 3: very few normal cells if any are left; most or
all cells are cancerous
The lower the grade, the slower a tumor will grow, and
the better the patient’s chance of survival. The higher the
grade, the quicker the tumor may grow or spread, and the
chances of survival are greatly diminished. In this case,
Stage III ovarian cancer has greatly
reduced the patient’s chances of recovery and/or
survival.
Stage groupings
The stage groupings are used to show the order of the
varied factors included in the TNM determination rating
system. Stage III groupings are as follows:
Stage III
Stage IIIa: T3a, N0, M0
Stage IIIb: T3b, N0, M0
Stage IIIc: T3c, N0, M0, or T(varied), N1, M0